Livros e Capítulos de Livros - LIM/35
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A coleção de Livros e Capítulos de Livros reúne capítulos e resumos de obras produzidas por autores do sistema FMUSP-HC que inclui a Faculdade de Medicina da Universidade de São Paulo (FMUSP), o Hospital das Clínicas da FMUSP e demais institutos associados.
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- 3.41 - Skin Barrier, Microbiome and Psoriasis(2022) HIRAYAMA, A. L. S. da; FONSECA, D. C.; ROMITI, R.Psoriasis is an inflammatory skin disorder of multifactorial etiology related to dysregulation of innate and adaptive immune responses, genetic inheritance and environmental factors. Skin and gut share features and functions. Each one has a singular ecosystem that interacts with epithelial and immune responses. The association of psoriasis with inflammatory bowel disease is well-documented, as well as immune and correlated inflammatory pathways. Recent studies have shown differences in the microbiome of psoriasis suggesting that the influence of gut and skin microbiome can possibly be related with the pathophysiology, disease's course and even its prognosis and treatment response. © 2022 Elsevier Inc. All rights reserved.
- New Technologies to Treat Obesity and Related Comorbidities(2023) BRUNALDI, V. O.; NETO, M. G.The escalating obesity pandemic has recently gained an appropriate neologism: globesity. Despite the accompanying growth of bariatric surgery worldwide, the number of patients with an indication for surgery still markedly outpaces the healthcare system’s capacity to offer treatment. Therefore, new technologies and novel alternatives are needed to help in addressing this global crisis. This chapter aims to review newly developed devices and procedures to treat excess weight and metabolic diseases, primarily type 2 diabetes. © SAGES 2023.
bookPart Câncer(2017) CAMPOS, Letícia De Nardi; HORIE, Lilian Mika; ALVES, Claudia C.; WAITZBERG, Dan L.bookPart Prefácio(2017) CARRILHO, Flair José; CECCONELLO, Ivan; D´ALBUQUERQUE, Luiz Augusto CarneirobookPart Câncer do esôfago - carcinoma epidermoide e adenocarcinoma(2017) SZACHNOWICZ, Sergio; MOTA, Filippe Camarotto; ALVES, Aline Marcílio; CECCONELLO, IvanbookPart Tratamento da diverticulite aguda complicada por abscesso(2017) ARAúJO, Sérgio Eduardo AlonsobookPart Apresentação(2018) MARIN, Márcia Lúcia de Mário; MALUVAYSHI, Cleide Harue; WAITZBERG, Dan LinetzkybookPart Avaliação e preparo do paciente para cirurgia bariátrica e metabólica(2023) GALVãO, André Luiz Vilela; RICCIOPPO, Daniel; PAJECKI, Denis; SANTO, Marco AureliobookPart Alterações no microbioma na obesidade e cirurgia bariátrica(2017) LAGO, Jalousie Pedro de Andrade; PAJECKI, Denis; SANTO, Marco AureliobookPart Técnicas endoscópicas para tratamento da obesidade(2023) MONTE JUNIOR, Epifanio Silvino do; MOURA, Eduardo Guimarães Hourneaux debookPart Cuidados pré e pós-operatórios do paciente bariátrico(2023) PAJECKI, Denis; DANTAS, Anna Carolina Batista; RICCIOPPO, Daniel; MARQUES, Fábio Israel Lima Castelo Branco; SANTO, Marco Aurelio- Cognitive and balance dysfunctions due to the use of zolpidem in the elderly: a systematic review(2021) TAVARES, Guilherme; KELMANN, Gizela; TUSTUMI, Francisco; TUNDISI, Catherine Nardini; SILVEIRA, Bárbara Regina Bruço; BARBOSA, Bruno Maximiliano Augusto Colombo; WINTHER, Diana Bragança; BOUTROS, Eduarda Conte; VILLAR, Gabriel dos Santos; BRUNOCILLA, Giovanna; LOURENÇÃO, Gustavo Rodrigues Caldas; FERREIRA, Jiulia Giovanna Aranha; BERNARDO, Wanderley MarquesABSTRACT. Zolpidem is one of the most widely prescribed hypnotic (non-benzodiazepine) agents for sleep disorder. Recently, an increase in the demand for this drug has been observed, mainly in the elderly population. Objective: This study aims to analyze the acute effect of zolpidem on cognitive and balance dysfunctions in the elderly population. Methods: A study was conducted by two independent researchers in four virtual scientific information bases and included randomized controlled trials. The studies evaluated elderly patients using zolpidem. Cognitive and balance dysfunctions were analyzed. Results: Six articles were included. The mean age of the participants in the studies was 69 years. The following zolpidem dosages were evaluated: 5, 6.25, 10, and 12.5 mg. Comparing zolpidem and placebo, relating to the cognitive dysfunctions, there is no statistically significant difference between the groups. However, in relation to balance dysfunctions, there is a statistically significant difference between the intervention and the comparison, favoring placebo. Conclusions: Zolpidem, even in usual doses (5 mg and 10 mg), has shown to increase the risk for balance dysfunctions. However, this does not occur in relation to cognitive changes.
- Endoscopic ultrasound-guided biliary drainage: a literature review(2023) DA-SILVA, RODRIGO RODA RODRIGUES; MAFRA, LUCAS GALLO DE ALVARENGA; BRUNALDI, VITOR OTTOBONI; ALMEIDA, LETÍCIA FRANÇA DE; ARTIFON, EVERSON LUIZ DE ALMEIDAABSTRACT Neoplasms of the biliopancreatic confluence may present with obstruction of the bile tract, leading to jaundice, pruritus and cholangitis. In these cases drainage of the bile tract is imperative. Endoscopic retrograde cholangiopancreatography (ERCP) with placement of a choledochal prosthesis is an effective treatment in about 90% of cases, even in experienced hands. In cases of ERCP failure, therapeutic options traditionally include surgical bypass by hepaticojejunostomy (HJ) or percutaneous transparietohepatic drainage (DPTH). In recent years, endoscopic ultrasound-guided biliary drainage techniques have gained space because they are less invasive, effective and have an acceptable incidence of complications. Endoscopic echo-guided drainage of the bile duct can be performed through the stomach (hepatogastrostomy), duodenum (choledochoduodenostomy) or by the anterograde drainage technique. Some services consider ultrasound-guided drainage of the bile duct the procedure of choice in the event of ERCP failure. The objective of this review is to present the main types of endoscopic ultrasound-guided biliary drainage and compare them with other techniques.
- Endoscopic therapeutic options for type 2 diabetes(2015) MOURA, E. G. H. De; ORSO, I. R. B.; MARTINS, B. C.; LOPES, G. S.The global obesity epidemic is expected to worsen with a concomitant increase in the comorbid conditions. Obesity is a major risk factor for type 2 diabetes, and it is not surprising that the global prevalence of this disease continues to increase. Given the emerging role of endoscopic procedures in the treatment of obesity and rapid changes in endoscopic technologies and techniques, this review considers the current state of endoscopic management of obesity and type 2 diabetes. Endoluminal interventions performed entirely through the gastrointestinal tract by using endoscopic devices offer the potential for an outpatient weight loss procedure that may be safer, less invasive, and more cost-effective, compared to current surgical approaches. Endoscopic techniques attempt to mimic some of the anatomic features of bariatric surgery and rely on gastric restriction and/or duodenal exclusion. In this chapter we will describe the two endoscopic methods that have much endorsement of the literature in relation to type 2 diabetes and are in current clinical use-the intragastric balloon and the duodenojejunal bypass liner. © Springer International Publishing Switzerland 2015.
- Disability in the post-obese bariatric patient: Old and new problems(2013) FAINTUCH, J.; SOUZA, S. A. F.; FABRIS, S. M.; ROSENBLATT, A.; CECCONELLO, I.Sustained and lifelong weight loss for severely obese people is not anymore an impossible dream, and a Swedish journal has described bariatric surgery as the fairy tale about the ugly duckling (Olbers 2011). Of course this is a bittersweet remark, because although for millions such is an advantageous and even life-saving intervention, all of them have to cope with the post-obesity status. Obesity is a chronic incurable disease and the postobesity status is an attenuated albeit ongoing illness, not a mere sequela. Appropriate follow-up and secondary interventions, be they surgical, clinical, physiatric, dietary, or psycho-social, may be demanded. Obesity entails widespread disorders involving as far away organs, structures, needs and abilities as the teeth, the central nervous system, the gut microbiome, the susceptibility to cancer, the performance at the workplace, and the demand for health care resources. Subsequent weight gain and comorbidity relapse is a permanent possibility, as endogenous and environmental obesogenic stimuli are not suppressed, only weakened. Gastrointestinal restriction and bypass are highly successful maneuvers when correctly indicated and conducted, however, they do not signal the end of the battle. Patients have to be educated and followed for life. It is hoped that such experience along with general public-health initiatives will eventually trickle down to their families, their offspring, and society in general, so that the new generations might be born and nurtured with obesity prevention in mind. © 2013 Springer-Verlag Berlin Heidelberg. All rights are reserved.
- Bariatric surgery: Current techniques and results(2013) FAINTUCH, J.; SOUZA, S. A. F.; FABRIS, S. M.; CECCONELLO, I.Half a century ago obesity was not a public health problem, however, gastroduodenal ulcers were ubiquitous. Many gastrectomies were conducted at that time and patients eventually lost weight. That is how bariatric surgery commenced, naturally expanding to a variety of techniques and accesses. Success has been both bigger and smaller than expected. Yes, bariatric operations became so popular that they already represent one of the five most performed major operations in some countries. They are followed by strong secondary benefits particularly concerning diabetes remission, to the point that a new subspecialty has arisen, metabolic surgery for diabetes. No, they are not carefree and they have not solved the problem of severe obesity, at least from the epidemiological point of view. They were actually not designed to be a mass treatment. The pursuit of new therapeutic avenues and the reinforcement of old ones is still mandatory, if the worldwide obesity epidemic is to be curtailed. © 2013 Springer-Verlag Berlin Heidelberg. All rights are reserved.
- Surgical options in type 2 diabetes(2015) PAJECKI, D.; RICCIOPPO, D.; KAWAMOTO, F.; SANTO, M. A.The onset of type 2 diabetes is characterized by a nonreversible complex cycle that includes severe deleterious effects on glucose metabolism. Obesity, but mainly visceral adipose tissue accumulation, is an important factor in this process. The goals of diabetes management in clinical practice, despite the improvement over the years, are often not met. In the last 20 years, based on observations of bariatric surgery series that have shown great improvement of type 2 Diabetes in morbid obese patients, metabolic surgery has emerged as a therapeutic possibility. In 2011 the International Diabetes Federation released its position statement mentioning that bariatric surgery was an accepted option for T2DM patients with BMI > 35 kg/m2 and might be considered an alternative therapy for patients with BMI ≤ 35 kg/m2 who do not respond to standard medical therapy. Metabolic/bariatric surgery includes the application of conventional bariatric procedures (Roux-en-Y gastric bypass, biliopancreatic diversion, sleeve gastrectomy) and the introduction of new procedures (ileal interposition, intestinal bipartition) designed with the specific aim of having metabolic effects, irrespective of causing massive weight loss. The reversal of T2DM occurs due to mechanisms such as the increase in insulin sensitivity associated with an improvement in beta-cell function, including recovering the first phase of insulin secretion. This recovery is a consequence of the increase of GLP-1 production, and change in circulating bile acids. Remission of diabetes is observed on the first postoperative days after the operation. © Springer International Publishing Switzerland 2015.
- Perspectives of surgery for benign esophageal diseases(2017) CECCONELLO, I.; BERNARDO, W. M.