Livros e Capítulos de Livros - LIM/13
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A coleção de Livros e Capítulos de Livros reúne capítulos e resumos de obras produzidas por autores do sistema FMUSP-HC que inclui a Faculdade de Medicina da Universidade de São Paulo (FMUSP), o Hospital das Clínicas da FMUSP e demais institutos associados.
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bookPart Ensaios clínicos(2023) LAUTERBACH, Gerhard da Paz; JúNIOR, Flávio Araújo BorgesbookPart Estudos observacionais(2023) JúNIOR, Flávio Araújo BorgesbookPart Testes diagnósticos(2023) JúNIOR, Flávio Araújo BorgesbookPart Suporte avançado de vida cardiovascular(2023) PINESI, Henrique Trombini; GIUGNI, Fernando RabiogliobookPart Suporte básico de vida(2023) PINESI, Henrique Trombini; GIUGNI, Fernando RabiogliobookPart Manejo das arritmias cardíacas(2023) DIAS, Roger Daglius; GIUGNI, Fernando Rabioglio; SCALABRINI NETO, AugustobookPart Angina refratária(2022) JúNIOR, Armindo Jreige; BALZAN, Hadrien Felipe Meira; GOWDAK, Luís Henrique WolffbookPart 0 Citação(ões) na Scopus The aquaretic effect of vasopressin V2 receptor antagonists(2013) GIRARDI, A. C. C.; CARRARO-LACROIX, L. R.; MORAIS, C. A. C. DeThe control of body osmolality is crucial for the maintenance of normal cell volume and can be accomplished by controlling water balance. The kidneys represent the major route for the elimination of water from the body, and water balance can be achieved without affecting the renal excretion of other electrolytes. In the kidney, the hormone arginine vasopressin (AVP) remarkably increases the permeability of the distal nephron to water by increasing the density of the water channel aquaporin 2 (AQP2). More specifically, AVP binds to its V2 receptor located at the basolateral membrane of the collecting duct cells, activates the cAMP/PKA signal transduction pathway and induces translocation of the AQP2 from cytoplasmic storage vesicles to the apical membrane. The development of bioavailable AVP antagonists with a high affinity for V2 receptors represents a promising approach for the treatment of hypervolemic and euvolemic hyponatremia due to its unique aquaretic effect. The goals of this chapter are to describe the physiology of vasopressin and the role of this hormone in water balance and to discuss the pharmacodynamics and pharmacokinetics of VAPTANS (nonpeptide vasopressin receptor antagonists), as well as their current and predictable therapeutic uses, based on recent data from pre-clinical studies and clinical trials. © 2013 Nova Science Publishers, Inc.- Experimental models for identifying target events in vascular injury(2021) GIRãO-SILVA, T.; MIYAKAWA, A. A.; LACCHINI, S.The development of experimental models represent an excellent tool for the study and understanding of arterial and venous injuries associated with vascular pathologies as diverse as atherosclerosis and transplant rejection. With these models it was possible to understand the interference of the environment on vascular biology as well as to identify the the role of several regulatory factors from the initiation to the formation of complex lesions as atherosclerosis. The increase in hemodynamic forces, especially flow and pressure, triggers endothelial damage in the vascular bed, leading to vascular remodeling and ultimately to graft failure. In this chapter, we describe several experimental models available for in vivo, in vitro, and ex vivo studies. So far, many advances have been made, but more research is still needed. Due to methodological limitations, a multipronged approach is necessary for a comprehensive understanding of the mechanisms involved with vascular diseases, especially in the processes of stenosis, restenosis, and venous graft occlusion. © 2021 Elsevier Inc. All rights reserved.
bookPart Fármacos utilizados no tratamento da isquemia miocárdica(2021) BORGES, Lígia Sayuri Teoi Coelho; JúNIOR, Flávio Araújo BorgesbookPart Fármacos antiarrítmicos(2021) MARCATTO, Leiliane Rodrigues; PESSENTE, Gabrielle D'Arezzo; SACILOTTO, LucianabookPart Fármacos anticoagulantes(2021) MARCATTO, Leiliane Rodrigues; TAVARES, Letícia Camargo; SACILOTTO, Luciana; SANTOS, Paulo Caleb Júnior de LimabookPart Fármacos que agem regulando a ação da vasopressina(2021) SANTOS, Danúbia Silva dos; LUCHI, Weverton Machado; GIRARDI, Adriana Castello CostabookPart Farmacogenômica(2021) TAVARES, Letícia Camargo; MARCATTO, Leiliane Rodrigues; SANTOS, Paulo Caleb Júnior de LimabookPart Fármacos utilizados no tratamento de anemias(2021) ALVARENGA, Aline Morgan; DINARDO, Carla Luana; SANTOS, Paulo Caleb Júnior de Limabook Livro-texto farmacologia(2021)bookPart Fármacos diuréticos(2021) RIOS, Thiago Matheus Santos; LUCHI, Weverton Machado; SANTOS, Acaris Benetti dos; MARTINS, Flávia Letícia; GIRARDI, Adriana Castello CostabookPart Cardiomiopatia Isquémica(2016) TSUTSUI, Jeane Mike; SBANO, João César Nunes; DOURADO, Luciana; GOWDAK, Luis Henrique Wolff; MATHIAS JUNIOR, WilsonbookPart Aspectos moleculares da hipertrofia dos músculos cardíaco e esquelético após treinamento fisico(2019) NóBREGA, Clara; ALVES, Guilherme Barretto; BRUM, Patricia Chakur; KRIEGER, José Eduardo; OLIVEIRA, Edilamar Menezes debookPart Taquiarritmias(2019) PEREIRA, Thiago Vicente; MARCHINI, Julio Flávio Meirelles