LUIS ARTHUR BRASIL GADELHA FARIAS

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LIM/49 - Laboratório de Protozoologia, Hospital das Clínicas, Faculdade de Medicina

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  • article 1 Citação(ões) na Scopus
    Case Report: Successful Treatment of Recurrent Urinary Tract Infection Due to Extensively Drug-Resistant Klebsiella Pneumoniae in a Kidney Transplant Recipient Using Chloramphenicol
    (2023) NETO, Lauro Vieira Perdigao; MACHADO, Anna Silva; SILVA, Riberto Garcia da; SOUZA, Ricardo Barbosa Cintra de; COUTINHO, Saurus Mayer; COMELLO, Florencia; PORTO, Ana Paula Matos; LIMA, Daila Sousa; GIOIA, Thais Sabato Romano di; LIMA, Victor Augusto Camarinha Castro; FARIAS, Luis Arthur Brasil Gadelha; MACEDO, Mariana Rolim Fernandes; NOGUERA, Saidy Liceth Vasconez; ANJOS, Sandra Nascimento dos; TONHEIRO, Chayenne Mika Matsumoto Pinto; COCENTINO, Brunno Cesar Batista; COSTA, Silvia Figueiredo; OLIVEIRA, Maura Salaroli de
    Effective therapies for multidrug-resistant (MDR) microorganisms, especially Gram-negative bacteria, are becoming rare. Also, solid-organ transplant recipients are at high risk of MDR Gram-negative bacilli infection. Urinary tract infections are the most frequent bacterial infections in kidney transplant recipients and are an important cause of mortality after renal transplantation. We describe a case of complicated urinary tract infection in a kidney transplant patient due to extensively drug-resistant (XDR) K. pneumoniae treated successfully with a regimen comprising a combination of chloramphenicol and ertapenem. We do not recommend chloramphenicol as a first-line choice for treating complicated urinary tract infections. Still, we believe it is an alterna-tive for infections caused by MDR and/or XDR pathogens in renal transplant patients, as other options are nephrotoxic.
  • article 0 Citação(ões) na Scopus
    Human Rabies during the COVID-19 Pandemic: Insights into Rabies Worldwide and Brazil
    (2024) FARIAS, Luis Arthur Brasil Gadelha; CAMINHA, Iusta; NETO, Lauro Vieira Perdigao; CAVALCANTI, Luciano Pamplona de Goes
    Human Rabies (HR) is a fatal zoonotic disease caused by lyssaviruses, with the rabies virus (RABV) identified as the causative agent. While the incidence of HR transmitted by dogs has decreased in Latin America, there has been a corresponding rise in transmission via wild animals. Given the lack of effective treatments and specific therapies, the management of HR relies on the availability of post-exposure prophylaxis and animal control measures. This review examines the dynamics and spread of HR during the global pandemic.
  • article 1 Citação(ões) na Scopus
    Streptococcus constellatus causing concomitant extra and intracranial abscesses complicated with sagittal sinus thrombosis
    (2023) FARIAS, Luis Arthur Brasil Gadelha; FIRMINO, Natalia Nogueira; SOUSA, Marcos Maciel; LIRA, Mateus Lavor; MEIRELES, Leonardo Nogueira; STOLP, Angela Maria Veras; MAIA, Kelma Maria; COSTA, Silvia Figueiredo; NETO, Lauro Vieira Perdigao
    Streptococcus constellatus is a gram-positive coccus member of the Streptococcus anginosus group (SAG). It can be found in the oral flora, and may cause abscess more commonly in the gastrointestinal tract, lungs, and heart. Brain abscesses are severe neurological infections with high mortality rates. Streptococcus species other than S. pneumoniae are rare causes of brain abscesses. This case report highlights a severe case of extra and intracranial abscesses due to S. constellatus in an immunocompetent host