LILIAN SCHAFIROVITS MORILLO
Índice h a partir de 2011
1
Projetos de Pesquisa
Unidades Organizacionais
Instituto Central, Hospital das Clínicas, Faculdade de Medicina
6 resultados
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bookPart Escalas(2019) SARAIVA, Marcos Daniel; ALIBERTI, Márlon Juliano Romero; SERRANO, Priscila Gonçalves; ONODERA, Eduardo Sho; APOLINARIO, Daniel; MAGALDI, Regina Miksian; FORTES FILHO, Sileno de Queiroz; MELO, Juliana de Araújo; ROTTA, Thereza Cristina Ariza; LIN, Sumika Mori; RANGEL, Luis Fernando; SILVA, Marina Maria Biella; APRAHAMIAN, Ivan; MAUER, Sivan; SIQUEIRA, Alaise Silva Santos de; MORILLO, Lilian Schafirovits; ARAúJO, Juliano Silveira de; STORNIOLO, Luana Vergian- Manejo das demências em fase avançada: recomendações do Departamento Científico de Neurologia Cognitiva e do Envelhecimento da Academia Brasileira de Neurologia(2022) BRUCKI, Sonia Maria Dozzi; APRAHAMIAN, Ivan; BORELLI, Wyllians Vendramini; SILVEIRA, Victor Calil da; FERRETTI, Ceres Eloah de Lucena; SMID, Jerusa; BARBOSA, Breno José Alencar Pires; SCHILLING, Lucas Porcello; BALTHAZAR, Márcio Luiz Figueiredo; FROTA, Norberto Anízio Ferreira; SOUZA, Leonardo Cruz de; VALE, Francisco Assis Carvalho; CARAMELLI, Paulo; BERTOLUCCI, Paulo Henrique Ferreira; CHAVES, Márcia Lorena Fagundes; NITRINI, Ricardo; SCHULTZ, Rodrigo Rizek; MORILLO, Lilian SchafirovitsABSTRACT Alzheimer’s disease (AD) and other neurodegenerative dementias have a progressive course, impairing cognition, functional capacity, and behavior. Most studies have focused on AD. Severe dementia is associated with increased age, higher morbidity-mortality, and rising costs of care. It is fundamental to recognize that severe dementia is the longest period of progression, with patients living for many years in this stage. It is the most heterogeneous phase in the process, with different abilities and life expectancies. This practice guideline focuses on severe dementia to improve management and care in this stage of dementia. As it is a long period in the continuum of dementia, clinical practice should consider non-pharmacological and pharmacological approaches. Multidisciplinary interventions (physical therapy, speech therapy, nutrition, nursing, and others) are essential, besides educational and support to caregivers.
- Accuracy of two prognostic indexes to predict mortality in older adults with advanced dementia(2022) LOPES, Beatriz Noele Azevedo; GARCEZ, Flavia Barreto; SUEMOTO, Claudia Kimie; MORILLO, Lilian SchafirovitsABSTRACT. Dementia is a cause of disability among older adults. Accessing advanced dementia prognosis is a challenge. Objective: The objective of this study was to evaluate the accuracy of the Charlson and Carey indexes in predicting 3-year survival of older adults with advanced dementia. Methods: This is a retrospective cohort study of 238 patients aged ≥60 years with advanced dementia from an outpatient clinic and classified as stage ≥6A by using the Functional Assessment Staging scale. We excluded patients with missing data. We reviewed the semi-structured interview (clinical, sociodemographic, and functional data) from the baseline visit. This information was used to calculate 3-year mortality risks according to the Charlson and Carey indexes. We used Cox proportional hazard models to evaluate the associations of all-cause mortality with both indexes, adjusted for sociodemographic variables. We used Harrell’s C measure to determine the discrimination. We calculated the absolute differences between observed and predicted 3-year mortality risks for each index for calibration. Results: In 238 patients, the average age was 80.5±7.8 years, with 36% being men. The median follow-up time was 1.8 years (0.05–3.0). The 3-year all-cause mortality rate was 50% (119 deaths). The Carey index was associated with mortality, with one point increase related to a 15% increase in the mortality risk (hazard ratio [HR]=1.15, 95% confidence interval (95%CI) 1.06–1.25, p=0.001), even after adjustment. Accuracy for the Charlson index and Carey index was 0.55 (95%CI 0.49–0.60) and 0.60 (95%CI 0.52–0.62), respectively, with no difference between them (p=0.44). Conclusions: Both indexes had poor discrimination and calibration performances in predicting 3-year mortality in patients with advanced dementia.
bookPart Introdução(2022) MOSCA NETO, Mario; UEHARA, Carlos André; ARECO, Flavia; CAçãO, João de Castilho; VELHO, José Carlos Aquino de Campos; MORIGUTI, Julio Cesar; MORILLO, Lilian Schafirovits; KAIRALLA, Maisa Carla; VENTURA, Mauricio de Miranda; GORZONI, Milton Luiz; HOJAIJ, Naira Hossepian Salles de Lima; BôAS, Paulo Jose Fortes Villas; MIRANDA, Roberto DischingerbookPart Envelhecimento e dependência(2022) VENTURA, Maurício de Miranda; MORILLO, Lilian Schafirovits; VELHO, José Carlos Aquino de CamposbookPart Demência avançada e estresse do cuidador(2019) MORILLO, Lilian Schafirovits; ARAúJO, Juliano Silveira de; STORNIOLO, Luana Vergian