Haemodynamic support for paediatric septic shock: a global perspective

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Citações na Scopus
4
Tipo de produção
article
Data de publicação
2023
DOI
Scopus
Web of Science
PubMed
Dimensions
Título da Revista
ISSN da Revista
Título do Volume
Editora
ELSEVIER SCI LTD
Autores
RANJIT, Suchitra
KISSOON, Niranjan
ARGENT, Andrew
INWALD, David
JABORINSKY, Roberto
SANKAR, Jhuma
NATRAJ, Rajeswari
OLIVEIRA, Claudio Flauzino De
Citação
LANCET CHILD & ADOLESCENT HEALTH, v.7, n.8, p.588-598, 2023
Projetos de Pesquisa
Unidades Organizacionais
Fascículo
Resumo
Septic shock is a leading cause of hospitalisation, morbidity, and mortality for children worldwide. In 2020, the paediatric Surviving Sepsis Campaign (SSC) issued evidence-based recommendations for clinicians caring for children with septic shock and sepsis-associated organ dysfunction based on the evidence available at the time. There are now more trials from multiple settings, including low-income and middle-income countries (LMICs), addressing optimal fluid choice and amount, selection and timing of vasoactive infusions, and optimal monitoring and therapeutic endpoints. In response to developments in adult critical care to trial personalised haemodynamic management algorithms, it is timely to critically reassess the current state of applying SSC guidelines in LMIC settings. In this Viewpoint, we briefly outline the challenges to improve sepsis care in LMICs and then discuss three key concepts that are relevant to management of children with septic shock around the world, especially in LMICs. These concepts include uncertainties surrounding the early recognition of paediatric septic shock, choices for initial haemodynamic support, and titration of ongoing resuscitation to therapeutic endpoints. Specifically, given the evolving understanding of clinical phenotypes, we focus on the controversies surrounding the concepts of early fluid resuscitation and vasoactive agent use, including insights gained from experience in LMICs and high-income countries. We outline the key components of sepsis management that are both globally relevant and translatable to low-resource settings, with a view to open the conversation to the large variety of treatment pathways, especially in LMICs. We emphasise the role of simple and easily available monitoring tools to apply the SSC guidelines and to tailor individualised support to the patient's cardiovascular physiology.
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URI
https://observatorio.fm.usp.br/handle/OPI/59262
Referências
  1. Andre-von Arnim AOV, 2021, PEDIATR CRIT CARE ME, V22, pE115, DOI 10.1097/PCC.0000000000002582
  2. Andreis DT, 2016, INTENS CARE MED, V42, P1387, DOI 10.1007/s00134-016-4249-z
  3. [Anonymous], 2021, WHO Model List of Essential Medicines - 22nd List, 2021
  4. [Anonymous], 2020, Sepsis
  5. [Anonymous], 2009, DENGUE GUIDELINES DI, DOI 10.1176/PN.41.1.0029B
  6. Argaiz ER, 2022, EUR HEART J-ACUTE CA, V11, P786, DOI 10.1093/ehjacc/zuac104
  7. Bakker J, 2022, INTENS CARE MED, V48, P148, DOI 10.1007/s00134-021-06595-9
  8. Banothu Kiran Kumar, 2023, Crit Care Explor, V5, pe0815, DOI 10.1097/CCE.0000000000000815
  9. Brossier DW, 2022, INTENS CARE MED, V48, P1691, DOI 10.1007/s00134-022-06882-z
  10. Bustos R, 2014, REV CHIL PEDIATR-CHI, V85, P539, DOI 10.4067/S0370-41062014000500003
  11. Byrne L, 2018, AM J RESP CRIT CARE, V198, P1043, DOI 10.1164/rccm.201801-0064OC
  12. Carrol ED, 2023, PEDIATR CRIT CARE ME, V24, pE263, DOI 10.1097/PCC.0000000000003263
  13. Chisti MJ, 2015, PLOS ONE, V10, DOI 10.1371/journal.pone.0139966
  14. Davis AL, 2017, CRIT CARE MED, V45, P1061, DOI 10.1097/CCM.0000000000002425
  15. Duke T, 2016, LANCET, V387, P721, DOI 10.1016/S0140-6736(16)00148-3
  16. El-Nawawy AA, 2018, J PEDIAT-BRAZIL, V94, P31, DOI 10.1016/j.jped.2017.02.005
  17. Fernández-Sarmiento J, 2023, PEDIATR CRIT CARE ME, V24, P213, DOI 10.1097/PCC.0000000000003123
  18. Fernández-Sarmiento J, 2022, J INTENSIVE CARE MED, V37, P753, DOI 10.1177/08850666211054444
  19. Fleischmann-Struzek C, 2018, LANCET RESP MED, V6, P223, DOI 10.1016/S2213-2600(18)30063-8
  20. George EC, 2015, BMC MED, V13, DOI 10.1186/s12916-015-0407-3
  21. Gilholm P, 2023, BMJ OPEN, V13, DOI 10.1136/bmjopen-2022-061431
  22. Hammond NE, 2022, NEJM Evid, V1, P5
  23. Hamzaoui O, 2020, J THORAC DIS, V12, pS72, DOI 10.21037/jtd.2019.12.50
  24. Han YY, 2003, PEDIATRICS, V112, P793, DOI 10.1542/peds.112.4.793
  25. Hanson J, 2014, CRIT CARE, V18, DOI 10.1186/s13054-014-0642-6
  26. Harley A, 2019, FRONT PEDIATR, V7, DOI 10.3389/fped.2019.00161
  27. Hazwani TR, 2020, CUREUS J MED SCIENCE, V12, DOI 10.7759/cureus.9981
  28. Hernandez G, 2022, INTENS CARE MED, V48, P1495, DOI 10.1007/s00134-022-06798-8
  29. Hippensteel JA, 2019, CRIT CARE, V23, DOI 10.1186/s13054-019-2534-2
  30. Iramain R, 2022, CUREUS J MED SCIENCE, V14, DOI 10.7759/cureus.30029
  31. Kattan Eduardo, 2022, Rev. bras. ter. intensiva, V34, P96, DOI [10.5935/0103-507x.20220004-pt, 10.5935/0103-507X.20220004-pt]
  32. Kattan E, 2022, J CRIT CARE, V71, DOI 10.1016/j.jcrc.2022.154070
  33. Kumar R, 2014, CRIT CARE MED, V42, P1775, DOI 10.1097/CCM.0000000000000298
  34. Lehr AR, 2022, PEDIATR CRIT CARE ME, V23, P181, DOI 10.1097/PCC.0000000000002890
  35. Levin M, 2019, LANCET RESP MED, V7, P581, DOI 10.1016/S2213-2600(19)30114-6
  36. Long E, 2018, PEDIATR CRIT CARE ME, V19, P513, DOI 10.1097/PCC.0000000000001534
  37. Maitland K, 2011, NEW ENGL J MED, V364, P2483, DOI 10.1056/NEJMoa1101549
  38. Marlais M, 2017, INTENS CARE MED, V43, P433, DOI 10.1007/s00134-016-4642-7
  39. Mawji A, 2021, PLOS ONE, V16, DOI 10.1371/journal.pone.0253051
  40. Mawji A, 2020, BMC HEALTH SERV RES, V20, DOI 10.1186/s12913-020-05344-w
  41. García MIM, 2015, INTENS CARE MED, V41, P1247, DOI 10.1007/s00134-015-3898-7
  42. Morin L, 2022, PEDIATRICS, V149, DOI 10.1542/peds.2021-052565
  43. Nallasamy K, 2020, INDIAN J CRIT CARE M, V24, P445, DOI 10.5005/jp-journals-10071-23445
  44. Natraj R, 2022, INDIAN J CRIT CARE M, V26, P863, DOI 10.5005/jp-journals-10071-24246
  45. Ni P, 2017, Int J Clin Med, V8, P412
  46. Obonyo NG, 2022, PEDIATR CRIT CARE ME, V23, P502, DOI 10.1097/PCC.0000000000002968
  47. Owen VS, 2021, CRIT CARE, V25, DOI 10.1186/s13054-021-03553-1
  48. Permpikul C, 2019, AM J RESP CRIT CARE, V199, P1097, DOI 10.1164/rccm.201806-1034OC
  49. Raman S, 2023, JAMA PEDIATR, V177, P122, DOI 10.1001/jamapediatrics.2022.4912
  50. Ramaswamy KN, 2016, PEDIATR CRIT CARE ME, V17, pE502, DOI 10.1097/PCC.0000000000000954
  51. Ranjit S, 2021, PEDIATR CRIT CARE ME, V22, pE448, DOI 10.1097/PCC.0000000000002714
  52. Ranjit S, 2018, INDIAN J CRIT CARE M, V22, P154, DOI 10.4103/ijccm.IJCCM_413_17
  53. Ranjit S, 2016, INDIAN J CRIT CARE M, V20, P561, DOI 10.4103/0972-5229.192036
  54. Ranjit S, 2014, PEDIATR CRIT CARE ME, V15, pE17, DOI 10.1097/PCC.0b013e3182a5589c
  55. Ranjit S, 2011, PEDIATR CRIT CARE ME, V12, P90, DOI 10.1097/PCC.0b013e3181e911a7
  56. Rudd KE, 2020, LANCET, V395, P200, DOI 10.1016/S0140-6736(19)32989-7
  57. Rudd KE, 2018, CRIT CARE, V22, DOI 10.1186/s13054-018-2157-z
  58. Samransamruajkit R, 2021, PEDIATR CRIT CARE ME, V22, P713, DOI 10.1097/PCC.0000000000002680
  59. Sankar J, 2017, PEDIATR CRIT CARE ME, V18, pE435, DOI 10.1097/PCC.0000000000001269
  60. Santhanam I, 2008, PEDIATR EMERG CARE, V24, P647, DOI 10.1097/PEC.0b013e31818844cf
  61. Schell Carl Otto, 2015, BMC Res Notes, V8, P313, DOI 10.1186/s13104-015-1275-9
  62. Schultz MJ, 2017, INTENS CARE MED, V43, P612, DOI 10.1007/s00134-017-4750-z
  63. Sinapidis D, 2018, BMC INFECT DIS, V18, DOI 10.1186/s12879-018-3156-z
  64. Southall DP, 2011, ARCH DIS CHILD, V96, P905, DOI 10.1136/archdischild-2011-300436
  65. Souza Daniela Carla, 2021, Rev. bras. ter. intensiva, V33, P231, DOI [10.5935/0103-507x.20210030, 10.5935/0103-507X.20210030]
  66. The United Nations, 2015, Sustainable development goals: 17 goals to transform our world
  67. Trunfio M, 2017, INFECTION, V45, P1, DOI 10.1007/s15010-016-0927-6
  68. Ventura AMC, 2015, CRIT CARE MED, V43, P2292, DOI 10.1097/CCM.0000000000001260
  69. Vieillard-Baron A, 2011, ANN INTENSIVE CARE, V1, DOI 10.1186/2110-5820-1-6
  70. Weiss Scott L, 2020, Pediatr Crit Care Med, V21, pe52, DOI [10.1097/PCC.0000000000002198, 10.1007/s00134-019-05878-6]
  71. White NJ, 2014, LANCET, V383, P723, DOI 10.1016/S0140-6736(13)60024-0
  72. WHO, 2016, Updated guideline: paediatric emergency triage, assessment and treatment: care of critically -ill children
  73. Wooldridge G, 2021, ANDES PEDIATRICA, V92, P954, DOI 10.32641/andespediatr.v92i6.4030
  74. Zampieri FG, 2020, AM J RESP CRIT CARE, V201, P423, DOI 10.1164/rccm.201905-0968OC

Coleções
Artigos e Materiais de Revistas Científicas - HU