Paradoxical Findings in Homozygous Familial Hypercholesterolemia in Japan: Longer Life But Still Not Totally Better!

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article
Data de publicação
2023
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ELSEVIER INC.
Citação
JACC: ASIA, v.3, n.6, p.892-894, 2023
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Resumo
Palavras-chave
genetics, homozygous familial hypercholesterolemia, low-density lipoprotein receptor, low-density lipoprotein–cholesterol, PCSK9
Referências
  1. Takeji Y., Tada H., Ogura M., Et al., Clinical characteristics of homozygous familial hypercholesterolemia in Japan: a survey using a national database, JACC: Asia, 3, 6, pp. 881-891, (2023)
  2. Cuchel M., Raal F.J., Hegele R.A., Et al., 2023 update on European Atherosclerosis Society consensus statement on homozygous familial hypercholesterolaemia: new treatments and clinical guidance, Eur Heart J, 44, pp. 2277-2291, (2023)
  3. Raal F.J., Santos R.D., Homozygous familial hypercholesterolemia: current perspectives on diagnosis and treatment, Atherosclerosis, 223, pp. 262-268, (2012)
  4. Endo A., A gift from nature: the birth of the statins, Nat Med, 14, pp. 1050-1052, (2008)
  5. Mabuchi H., Half a century tales of familial hypercholesterolemia (FH) in Japan, J Atheroscler Thromb, 24, pp. 189-207, (2017)
  6. Watts G.F., Gidding S.S., Hegele R.A., Et al., International Atherosclerosis Society guidance for implementing best practice in the care of familial hypercholesterolaemia, Nat Rev Cardiol, 20, pp. 845-869, (2023)
  7. Alves A.C., Alonso R., Diaz-Diaz J.L., Et al., Phenotypical, clinical, and molecular aspects of adults and children with homozygous familial hypercholesterolemia in Iberoamerica, Arterioscler Thromb Vasc Biol, 40, pp. 2508-2515, (2020)
  8. Tromp T.R., Hartgers M.L., Hovingh G.K., Et al., Worldwide experience of homozygous familial hypercholesterolaemia: retrospective cohort study, Lancet, 399, pp. 719-728, (2022)
  9. Cuchel M., Lee P.C., Hudgins L.C., Et al., Contemporary homozygous familial hypercholesterolemia in the United States: insights from the CASCADE FH registry, J Am Heart Assoc, 12, (2023)
  10. Raal F.J., Pilcher G.J., Panz V.R., Et al., Reduction in mortality in subjects with homozygous familial hypercholesterolemia associated with advances in lipid-lowering therapy, Circulation, 124, pp. 2202-2207, (2011)
  11. Santos R.D., Expression of LDLRs (low-density lipoprotein receptors), dyslipidemia severity, and response to PCSK9 (proprotein convertase subtilisin kexin type 9) inhibition in homozygous familial hypercholesterolemia: connecting the dots, Arterioscler Thromb Vasc Biol, 38, pp. 481-483, (2018)
  12. Nohara A., Yagi K., Inazu A., Kajinami K., Koizumi J., Mabuchi H., Absence of familial defective apolipoprotein B-100 in Japanese patients with familial hypercholesterolaemia, Lancet, 345, (1995)