LIM/20 - Laboratório de Terapêutica Experimental

URI Permanente desta comunidade

https://observatorio.fm.usp.br/handle/OPI/3674
O Laboratório de Terapêutica Experimental é ligado ao Departamento de Clínica Médica da Faculdade de Medicina da Universidade de São Paulo (FMUSP).

Linhas de pesquisa: fisiopatologia da asma brônquica; mecanismo de lesão pulmonar e educação médica.

Site oficial: http://limhc.fm.usp.br/portal/lim20-laboratorio-de-terapeutica-experimental/

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Risk Factors for the Impairment of Ambulation in Older People Hospitalized with COVID-19: A Retrospective Cohort Study
(2023) SILVA, E. C. G. E.; SCHMITT, A. C. B.; GODOY, C. G. de; OLIVEIRA, D. B. de; TANAKA, C.; TOUFEN, C. Jr.; CARVALHO, C. R. R. de; CARVALHO, C. R. F.; FU, C.; HILL, K. D.; POMPEU, J. E.
(1) Background: Some older people hospitalized with COVID-19 have experienced reduced ambulation capacity. However, the prevalence of the impairment of ambulation capacity still needs to be established. Objective: To estimate the prevalence of, and identify the risk factors associated with, the impairment of ambulation capacity at the point of hospital discharge for older people with COVID-19. (2) Methods: A retrospective cohort study. Included are those with an age > 60 years, of either sex, hospitalized due to COVID-19. Clinical data was collected from patients’ medical records. Ambulation capacity prior to COVID-19 infection was assessed through the patients’ reports from their relatives. Multiple logistic regressions were performed to identify the risk factors associated with the impairment of ambulation at hospital discharge. (3) Results: Data for 429 older people hospitalized with COVID-19 were randomly collected from the medical records. Among the 56.4% who were discharged, 57.9% had reduced ambulation capacity. Factors associated with reduced ambulation capacity at discharge were a hospital stay longer than 20 days (Odds Ratio (OR): 3.5) and dependent ambulation capacity prior to COVID-19 (Odds Ratio (OR): 11.3). (4) Conclusion: More than half of the older people who survived following hospitalization due to COVID-19 had reduced ambulation capacity at hospital discharge. Impaired ambulation prior to the infection and a longer hospital stay were risks factors for reduced ambulation capacity.
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Aerobic Exercise Effects in Severe Asthma: Involvement of Lung Fibroblast (MRC-5) Cells and Kinins Signaling
(2021) BRANDAO-RANGEL, Maysa A. Rodrigues; MORAES-FERREIRA, Renilson; SILVA-REIS, Anamei; PALMEIRA, H. S. Palmeira; ALMEIDA, Francine M.; OLIMPIO, R. S. Olimpio; ZAMARIOLI, Lucas S.; OLIVEIRA, Carlos R.; DAMACENO-RODRIGUES, Nilsa R.; PESQUERO, Joao B.; AIMBIRE, Flavio; VIEIRA, Rodolfo De Paula
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Green Areas and PM2,5 exposure could be associated with Asthma and COPD?
(2023) ALMEIDA, Francine Maria; MOREIRA, Tiana Carla Lopes; OLIVEIRA, Lucas Miranda; RIGHETTI, Renato Fraga; LOPES, Fernanda Degobbi Tenorio Quirino Santos; ALENCAR, Airlane P.; GOUVEIA, Nelson; MAUAD, Thais; LOTUFO, Paulo A.; BENSENOR, Isabela; SANTOS, Itamar Souza; TIBERIO, Iolanda Fatima Lopes Calvo
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High-intensity interval training (HIIT) versus constant-load exercise (CLE) on the short-acute beta agonist (SABA) consumption and peak-expiratory flow (PEF) in subjects with moderate to severe asthma
(2023) SILVA, Ronaldo Aparecido Da; FERNANDES, Thiago; STELMACH, Rafael; CUKIER, Alberto; CARVALHO-PINTO, Regina Maria; CARVALHO, Celso R. F.
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Occupational asthma and allergic asthma: differences in the physical activity level, clinical control, and airway inflammation
(2023) SILVA, Ronaldo Aparecido Da; FREITAS, Lucas Rodrigues Silva; ALMEIDA, Francine Maria De; GALVAO, Clovis Eduardo Santos; NOGUEIRA, Soraia Felix; BEZERRA, Suellen Karoline Moreira; CARVALHO, Celso Ricardo Fernades De; ARAUJO, Kaique Alves De; CRUZ, Fabiola Matos Da; AGONDI, Rosana Camara; MARTINS, Milton Arruda; TIBERIO, Iolanda De Fatima Lopes Calvo; SARAIVA-ROMANHOLO, Beatriz Mangueira
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Asthma in Brazil: an epidemiological analysis from 2008 to 2021
(2023) PINHEIRO, David Halen Araujo; SOUZA, Joao Victor Hermogenes De; LIMA, Fabiano Francisco De; JUSTO, Alberto Fernando Oliveira; CERVERA, Vitoria Zacarias; CARVALHO-PINTO, Regina Maria; CARVALHO, Celso R. F.
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Diaphragmatic mobility assessed by ultrasound is associated with thoracoabdominal asynchrony in severe to very severe COPD patients
(2023) SANTOS, Juliana M. B.; REIS, Estefane C. M.; LINO, Pedro L.; LUNARDI, Adriana C.; SILVA, Cibele C. B. M.; PINTO, Thiago F.; CARVALHO-PINTO, Regina M.; CUKIER, Alberto; CHAMMAS, Maria C.; CARVALHO, Celso R. F.
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Effects of an online behaviour change intervention to promote physical activity in adults with asthma: preliminary data of a randomized controlled trial
(2023) OLIVEIRA, Joice Mara; PEDROSO, Ariele; CORREIA, Natielly Soares; MELO, Denner Ildemar Feitosa; BIDOIA, Caroline Sydloski; PITTA, Fabio; KARLOH, Manuela; MATIAS, Thiago Sousa; LIMA, Fabiano Francisco; CUNHA, Marieta Cabral Amaral Da; CARVALHO, Celso R. F.; FURLANETTO, Karina Couto
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Clinical, demographic and functional evaluation of patients with hypersensitivity pneumonitis and their comparison based on current diagnostic criteria
(2023) BRIDI, Guilherme Das Posses; SILVA, Bianca Freire Da; CUNHA, Marieta Cabral Amaral Da; QUEIROZ, Douglas Silva; ALVES- JR., Jose Leonidas; SALGE, Joao Marcos; CARVALHO, Celso R. F. De; KAIRALLA, Ronaldo Adib; SOUZA, Rogerio De; BALDI, Bruno Guedes
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Aging predictive factors for oxygenation response and mortality in COVID-19 and acute respiratory distress syndrome (ARDS) patients exposed to prone position: A multicenter cohort study
(2023) CABRAL, Marieta; CUNHA, Amaral; LUNARDI, Adriana C.; SCHARDONG, Jociane; RIGHI, Natiele C.; SANT'ANNA, Guadalupe N.; ISENSEE, Larissa P.; XAVIER, Rafaela F.; POMPEU, Jose E.; WEIGERT, Ranata M.; MATTE, Darlan L.; CARDOSO, Rozana A.; ABRAS, Ana C. V.; SILVA, Antonio M. V.; DORNELES, Camila C.; WERLE, Roberta W.; STARKE, Ana C.; PLENTZ, Rodrigo D. M.; FERREIRA, Juliana C.; CARVALHO, Celso R. F.