Generation of four induced pluripotent stem cells lines from PBMC of the DFNA58 family members: Two hearing-impaired duplication carriers (USPi006-A e USPi007-A) and two normal-hearing noncarriers (USPi004-A and USPi005-A)
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Citações na Scopus
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Tipo de produção
article
Data de publicação
2023
Título da Revista
ISSN da Revista
Título do Volume
Editora
ELSEVIER
Autores
KOBAYASHI, Gerson S.
VARELLA-BRANCO, Elisa
MOREIRA, Danielle P.
KITAJIMA, Joao Paulo F. W.
HEMZA, Claudia R. M. L.
MINGRONI-NETTO, Regina C.
LOJUDICE, Fernando H.
Citação
STEM CELL RESEARCH, v.71, article ID 103181, 5p, 2023
Resumo
The DFNA58 locus contains a genomic duplication involving three protein-coding genes (CNRIP1, PLEK, and PPP3R1 & PRIME;s exon 1) and other uncharacterized lncRNA genes (LOC101927723, LOC107985892 and LOC102724389). To clarify the role of these genes in hearing and precisely determine their role in hearing loss, four iPSC lines were generated from two carriers and two noncarriers of the duplication.
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Referências
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